This condition affects up to 1 % of the male population. Peyronie's disease is the presence of fibrous plaques within the shaft of the penis. The plaques are formed in the tissue surrounding the main erectile bodies, the Tunica Albuginea, thus with erections the plaque will cause bending and angulation of the penis. Sometimes the bending is so marked that it makes sexual intercourse impossible.The exact cause is not yet fully understood and many factors are thought to be involved. There may in some cases be a family history or the patient themselves have Dupuytren's Contracture, where there are similar fibrotic plaques in the palm of the hand. The condition can affect men of any age and present with varying degrees of curvature and severity, which is most visible when the penis is erect.